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The baseline clinical toxicity threshold is approximately 45 mg/kg. Doses approaching or exceeding 5x this threshold represent critical or life-threatening exposure.
Primary mechanism: Exothermic hydration reaction causing oral chemical burns and hypercalcemia. Symptoms typically manifest in gastrointestinal, cardiovascular, or central nervous systems depending on absorbed bioavailability.
Emesis must NEVER be induced if the patient is already showing neurological symptoms (ataxia, tremors, seizures), is comatose, has ingested caustic/corrosive agents, or is a species incapable of vomiting (e.g., horses, rabbits, rodents).